AADR Oral Health Effects of Tobacco Products:
Science and Regulatory Policy

 

 

Funding for this conference is made possible, in part, by the Food and Drug Administration through grant (1R13FD006142). Views expressed in written materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does any mention of trade names, commercial practices, or organization imply endorsement by the United States Government. 

View the full agenda for this meeting below and read the speaker bios online. This conference was recorded and will be in our IADR CE On Demand Library for all IADR members in the coming month. 

Time

Activity

7:30 a.m.

Registration Opens
Registered attendees can pick up name badges in Regency IV foyer

8 a.m.

Continental Breakfast Available

 

Introduction
Session Chair: A. Seun Ajiboye, Director of Science Policy and Government Affairs, American Association for Dental Research, Alexandria, Va.

8:30 a.m.

Welcome and Opening Remarks
Does Oral Health Matter?
Raul I. GarciaBoston University Henry M. Goldman School of Dental Medicine, Mass.

 

Session I: Perspectives on Tobacco Regulatory Policy
Session Chair: Elizabeth Kaye, Boston University Henry M. Goldman School of Dental Medicine, Mass.

 

Objective: This session will be used to educate the audience about FDA tobacco regulatory policy and how science is used during the regulatory process. 

8:45 a.m.

FDA’s Plan for Tobacco Regulation and Efforts Around Oral Health
Mitch Zeller, Food and Drug Administration Center for Tobacco Products, Silver Spring, Md.

9:05 a.m.

Regulation of Tobacco Products in a Dynamically Changing Market: Protecting the Public/Oral Health from Harm and Addiction
Greg Connolly, Northeastern University Bouvé College of Health Sciences and School of Law, Boston, Mass.

 9:25 a.m.

Discussion

 

Session II: Combusted Tobacco (Inhaled and non-inhaled) Products
Session Chair: Raul I. Garcia, Boston University Henry M. Goldman School of Dental Medicine,  Mass.

 

Objective: Speakers will give presentations on the oral health effects of smoked or combustible tobacco products regulated by the FDA, including hookah, cigarettes/roll-your-own tobacco, cigars and pipe tobacco.

9:40 a.m.

Chemical Carcinogenesis of Combustible Tobacco Product Ingredients
Stephen Hecht, University of Minnesota Medical School, Minneapolis

10:00 a.m.

Effect of Combustible Tobacco Products on Mucosal Immunity
Ilona Jaspers, University of North Carolina-Chapel Hill School of Medicine

10:20 a.m.

Discussion

10:35 a.m.

Break

 

Session III: Non-combusted Tobacco (Smokeless Tobacco)
Session Chair: Purnima Kumar, The Ohio State University College of Dentistry, Columbus

 

Objective: Speakers will give presentations on the oral health effects of non-smoked or non-combustible tobacco products regulated by the FDA, including dissolvable tobacco, snuff, snus and chewing tobacco. Speakers will be asked to evaluate claims of modified or reduced risk where applicable with respect to the oral cavity.

10:45 a.m.

Smokeless Tobacco Products: Oral Health Effects, Flavor and Regulatory Implications
Scott L. Tomar, University of Florida College of Dentistry, Gainesville

11:05 a.m.

Effect of Smokeless Tobacco Product Ingredients on the Oral Microbiome
Richard L. Gregory, Indiana University School of Dentistry, Indianapolis

11:25 a.m.

Smokeless Tobacco Constituents: Carcinogenicity and Variations Across Products
Irina Stepanov, University of Minnesota School of Public Health, Minneapolis

11:45 p.m.

Discussion

12:00 p.m.

Lunch*

 

Session IV: Novel Nicotine Delivery Systems
Session Chair: Christopher H. Fox, Chief Executive Officer, American Association for Dental Research, Alexandria, Va.

 

Objective: Speakers will give presentations on the oral health effects of electronic nicotine delivery systems (ENDS). Speakers will be asked to evaluate claims of modified or reduced risk where applicable with respect to the oral cavity. Because ENDS are relatively new products, identifying research and regulatory gaps will be especially important in this session.

1:00 p.m.

Novel Nicotine Delivery Systems and Their Impact on Oral Health: The Case of e-cigarettes 
Pamela I. Clark, University of Maryland School of Public Health, College Park
Marielle C. Brinkman, The Ohio State University College of Public Health, Columbus

1:20 p.m.

Electronic Cigarettes exacerbate the virulence potential of the subgingival microbiome
Purnima Kumar, The Ohio State University College of Dentistry, Columbus

1:40 p.m.

Novel Nicotine Delivery Systems: Effects of e-cigarette Aerosol on Epithelial Cells, Oral Microbiome and Novel Research Questions on Effects of e-cigarettes on the Oral Cavity
Deepak Saxena, New York University College of Dentistry, New York

2:00 p.m.

Discussion

 

Session V: In Vitro Models, Standards and Experimental Methods
Session Chair: Deepak Saxena, New York University College of Dentistry, New York

 

Objective: Speakers will give presentation about appropriate models and experimental methods for testing toxicity of tobacco products on the oral cavity. This will be especially important for accurate testing of new tobacco products. This session is also timely given the FDA’s current review of using higher order mammals in tobacco research.  This session will address the merits of various testing methods and models.

2:15 p.m.

E-cigarette Testing Devices and Reference Materials
Jeffrey Kim, American Dental Association Foundation Volpe Research Center, Gaithersburg, Md.

2:35 p.m.

Human-relevant In Vitro Test Systems for Evaluation of Oral Exposures
Holger Behrsing, Institute for In Vitro Sciences, Gaithersburg, Md.

2:55 p.m.

Mouse Models of Tobacco-induced Lung Disease
Terry Gordon, New York University School of Medicine, New York

3:15 p.m.

Development of Animal Models of Oral Health Effects of Tobacco Products
Tara Aghaloo, University of California, Los Angeles School of Dentistry

3:35 p.m.

Discussion

3:50 p.m.

Break

 

Conference Summary and Next Steps
Session Chair: Christopher H. Fox, Chief Executive Officer, American Association for Dental Research, Alexandria, Va.

4:00 p.m.

The Role of Dentistry in Tobacco Use Cessation
Judith S. Gordon, University of Arizona College of Nursing, Tucson

4:20 p.m.

Overall Discussion

4:50 p.m.

Conference Summary and Next Steps
Raul I. GarciaBoston University Henry M. Goldman School of Dental Medicine, Mass.

5:30 p.m.

Adjourn

5:30 p.m.

Reception*

*No FDA funds will be used towards food or beverages for the conference.


Funding for this conference is made possible, in part, by the Food and Drug Administration through grant (1R13FD006142). Views expressed in written materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does any mention of trade names, commercial practices, or organization imply endorsement by the United States Government.

The International Association for Dental Research is an ADA CERP Recognized Provider. ADA CERP is a service of the American Dental Association to assist dental professionals in identifying quality providers of continuing dental education. ADA CERP does not approve or endorse individual courses or instructors, nor does it imply acceptance of credit hours by boards of dentistry. Concerns or complaints about a CE provider may be directed to the provider or to ADA CERP at www.ada.org/cerp.

The maximum number of continuing education credits available for this meeting is 7 hours.