Featured Presentations

Wednesday, September 10, 2014
13:30 – 15:00

Periodontitis, Diabetes and Atherosclerotic Cardiovascular Disease: Epidemiology, Genes and Therapy
Organizer: Bruno Loos (University of Amsterdam, Netherlands)
Sponsor: Sunstar
Location: Lacroma Hotel, Elafiti Room 3

Description: Periodontitis (PD), diabetes and atherosclerotic cardiovascular disease (ACVD) are complex diseases and are associated with each other. However possible causative mechanisms of these links are not yet clear. We will first outline the epidemiological links between PD, diabetes and CVD, from both a causative and from a sequel point of view. Next we will discuss genetic backgrounds for these three diseases and the possible overlap in causative genes/loci between them. Recent studies identified ANRIL as a major genetic risk factor of PD and CVD. The function of ANRIL showed a trans-regulatory role for the adiponectin receptor 1 (ADIPOR1), the fatty acid desaturase (FADS) gene cluster and the vesicle-associated membrane protein VAMP 3, which underlines mechanisms of lipid and glucose metabolism as important links to the shared disease etiology of PD, CVD and diabetes. To further map a more complete spectrum of genetic risk variants for PD, we search for new candidate genes. We employ quantitative trait loci (QTL) mapping strategies in mouse recombinant inbred lines (RILs) of the Collaborative Cross, to identify possible human risk loci. Further we present updated meta-analyses on treatment of PD in diabetic - and nondiabetic PD patients, and similarly for ACVD - and non-ACVD PD patients. Clearly the literature indicates that favorable clinical effects on the cardiovascular system and on biomarkers are apparent, for all such patients and especially for those with PD and co-morbidities, making PD therapy for those with diabetes or ACVD very beneficial.

Bio-inspired Synthesis of Mineralized Tissues
Organizer: Paul Anderson (Queen Mary University of London, England)
Sponsored by: BSODR-MINTIG
Location: Lacroma Hotel, Divona Room 1 & 2

Description: The extracellular cellular environment is now recognized to be crucial for tissue engineering of mineralized tissues.  During bone and dentine formation cues given to the cells by this extracellular environment drive optimal tissue formation.  The application of these bio-inspired concepts are becoming increasingly integrated into tissue engineering approaches.  This symposium seeks to capture the excitement of this burgeoning field through presentation of current research that show promise (new tools) for reparative dentistry.  Planned talks included consideration of the natural process for mineralized tissue formation with new information on novel signaling proteins and processes that can be harnessed for assisting mineralized tissue synthesis.  The program also intends to consider current advances in biomimetic materials such as self-assembling peptides and bio-inspired ceramics providing customized scaffold for promotion of tissue synthesis. The symposium will be of interest to basic, applied and clinical scientists in reviewing the ever-expanding tissue engineering field and is intended to promote cross-disciplinary fertilization of discussion and new ideas in this emerging field. The symposia will also provide depth of knowledge for early stage researchers in developing understanding in the tissue engineering field or in expanding continual professional development.

Thursday, September 11, 2014
8:00 – 9:30

Understanding Professionalism in Dentistry – Concepts and Conflicts
Organizer: Jennifer E. Gallagher (King’s College London, England)
Sponsored by: Behavioral, Epidemiologic and Health Service Research
Location: Lacroma Hotel, Divona Room 1 & 2

Description: Professionalism within medicine has been the subject of intense inquiry in recent years, resulting in a valuable body of knowledge. Both medicine and dentistry describe professionalism as an essential competence, but should dentistry rely on medicine to provide this knowledge, or are there distinct differences with dentistry, which need to be taken into consideration? It is important to reflect on definitions of professionalism and its application to dentistry across different settings and countries.

The symposium will explore the student journey from ‘idealism’ about dentistry to ‘realism’ over the five year dental programme. Research into the perspective of academic teachers, patients, and students provide insight into changes in student perceptions over time, and possible influences.  

Finally the symposium will provide the opportunity to consider the tension between the individual and the system; real world environments bring a range of pressures to bear on dental professionals who are increasingly working in teams and dental systems, thus impacting on how professionalism in practice is manifest.

There will be an opportunity for discussion and debate over the implications for education and research.

Oral Prevention in the Context of Systemic Diseases
Organizer: Lior Shapira (Hadassah Medical Center, Israel)
Sponsor: Proctor & Gamble
Location: Lacroma Hotel, Elafiti Room 3

Description: During the last 20 years, there is a growing interest in associations between periodontitis and chronic systemic disorders.  The hypothesis that periodontitis may be a risk factor for other diseases was based on studies which show that periodontal diseases may be associated with an increased risk of premature death. Many human and animal studies had investigated periodontitis as a risk factor for cardiovascular diseases (including atherosclerosis, stroke and coronary heart disease), adverse pregnancy outcomes and diabetes.  These relationships between periodontitis and systemic pathologic conditions are probably due to the nature of periodontitis as a chronic local inflammatory disease initiated by infection and these two processes can affect distant organs. The distant effect can be induced by metastasis of the infection (bacteremia), effect of inflammatory mediators and cells that cause systemic inflammation, activation of systemic innate and adaptive immunity, or a combination of these potential mechanisms. However, an important question is whether periodontal therapy and prevention measures can reduce the rates of these serious systemic conditions. The purpose of this symposium is to assess the state of the science regarding the association of periodontitis with cardiovascular disease, diabetes and adverse pregnancy outcomes, and to evaluate if periodontal therapy/prevention may have an impact on these conditions.

Thursday, September 11, 2014
10:45 – 12:15

Peri-Impant Disease: A New Challenge
Organizer: Liran Levin (Rambam Health Care Campus, Israel)
Sponsor: Silonite® & Implantology Research
Location: Lacroma Hotel, Divona Room 1 & 2

Description: During the last years, the use of dental implants is becoming a common practice and peri-implant diseases are more frequently evident. Apparently, as time goes by and also implies from the available literature, we will be seeing more and more cases of peri-implant diseases. The reported prevalence in the literature reaches almost 30 to 50% of implant patients. This means that one out of two or three of our implant patients might present with peri-implant disease at some point. This is also an important aspect of informed consent for our patients. Another troubling issue with regards to peri-implant diseases is the lack of appropriate, well-documented gold-standard treatment, specifically for peri-implantitis. There are many suggested treatment options described in case reports and case series in the literature; none of them seems to provide a predictable long-term resolution of the disease.

In order to prevent and treat peri-implant diseases, there is  a need to understand the nature of the disease and the risk factors.

Is Dentine Hypersensitivity a Public Health Problem?
Organizer: Peter Robinson (University of Sheffield, England)
Sponsor: GlaxoSmith Kline and Behavioral, Epidemiologic and Health Services Research
Location: Lacroma Hotel, Elafiti Room 3

Description: A disease can be considered to constitute a public health problem if it is widespread or serious, if it carries severe consequences or costs to the population or individuals and if there are effective methods available to prevent alleviate or cure it.

Using this framework, this workshop will explore current understanding of Dentine Hypersensitivity in the form of a debate.  Prof Peter Robinson will outline the definition of a public health problem and the next two speakers will make the case for Dentine Hypersensitivity meeting these criteria.  Dr Bekes will describe the prevalence of the condition and consider its prevention and treatment. A key focus of the symposium will be a focus on emerging understanding of the psychosocial consequences of Dentine Hypersensitivity by Dr Sarah Baker. Finally, Professor Ivor Chesnutt will review the evidence to make the case against regarding Dentine Hypersensitivity as a public health problem.

The speakers will share their presentations in advance to ensure that the debate is coherent. In total therefore, the workshop will critically appraise the evidence pertaining to the prevalence of the disease, therapies for it, its impact and its importance.

Friday, September 12, 2014
8:00 – 9:30

The Oral Health of Older People: Developing a Research Agenda
Organizer(s): Steve Turner (University of Edinburgh, Scotland) and Angus Walls (University of Edinburgh, Scotland)
Sponsored by: GlaxoSmith Kline and Behavioral, Epidemiologic and Health Services Research
Location: Lacroma Hotel, Divona Room 1 & 2

Description: The EU population aged 80 and over is forecast to rise to over 25.5m by 2015.  While it should not be assumed that all are necessarily dependent or in poor health, it is likely that poor oral health and care are high risks for this age group.  The symposium would seek to identify gaps in evidence in the epidemiology of poor oral health in this group, what is needed to improve it, and how best to translate evidence to practice and policy.  These issues remain relatively low on the research agenda, as indicated by The WHO Global Oral Health Programme:

...  compared with the situation for other age groups there is a remarkable shortage of published research papers reporting results of oral health intervention programmes … both in relation to efficacy analysis (demonstrated in RCTs) and effectiveness (demonstrated in community trials). Petersen et al, Comm Dent Oral Epid, 2005, 33, p85

The symposium will address the following themes:

  • Systemic disease and oral health
  • Oral function and its maintenance
  • Oral hygiene, self care and carer care
  • Quality of life
  • Oral health and cognitive decline
  • Barriers and facilitators to good oral health relating to service provision, cost, training, formal and informal carers, including the impact of different contractual arrangements.

Caries Infiltration
Organizer: Hendrik Meyer-Lueckel (RWTH Aachen University, Germany)
Sponsor: DMG Hamburg & Cariology Research
Location: Lacroma Hotel, Elafiti Room 1 & 2

Description: The caries process is nowadays mainly managed by either non-invasive (fluoridation and oral hygiene education) or invasive (restoration) interventions. Besides, as an almost non-invasive option sealants have been used mainly for occlusal surfaces fissure for many years. Caries infiltration is a relatively new micro-invasive approach to deal with caries lesions at both proximal and smooth surfaces. In contrast to sealing, caries infiltration aims to penetrate the lesion body of enamel caries lesions with so called infiltrants. After curing, the resin infiltrant occludes the lesion pores and thus prevents from further demineralization. In this symposium the paradigm shift from a rather invasive to a minimum interventional strategy to treat caries lesions will be highlighted. Consequences hereof regarding diagnostics and treatment planning will be presented. Moreover, development of the infiltration technique, its clinical feasibility and efficacy for the treatment of proximal surfaces of posterior teeth will be addressed. An insight into possible further indications (fissure caries, cavitated lesions, MIH teeth) will be given. Evidence for the well-established technique of infiltration of aesthetically relevant caries lesions will be presented.

Friday, September 12, 2014
10:45 - 12:15

Food and Saliva – Role of Saliva in the Eating Process
Organizer: Anne Marie Lynge Pedersen (University of Copenhagen, Denmark)
Sponsor: GlaxoSmith Kline
Location: Lacroma Hotel, Bokar Room

Description: Symposium on the latest update on the interaction between saliva and food, and the role of saliva in the process of eating including formation of food bolus, swallowing, taste perception and other oral food perceptions.

Saturday, September 13, 2014
8:30 – 10:00

Treating Caries – the Evidence, the Users, the Society
Organizer: Falk Schwendicke (Charité - Universitätsmedizin Berlin, Germany)
Sponsor: DMG Hamburg and Cariology Research
Location: Lacroma Hotel, Elafiti  Room 3

Description: Being the most prevalent disease worldwide, dental caries is increasingly concentrated in those already disadvantaged and poor. Thus, current and -even more so- new treatments might be efficacious, but not applicable in these patients due to practical and economic limitations. Thus, treatments of caries should be evaluated in terms of their clinical health benefits, but also their applicability, their impact on patients’ subjective well-being, their costs and their effects on the distribution of health benefits between different populations and countries. The planned symposium will evaluate the clinical evidence for when and how to treat caries lesions, and assess both patient- and dentist-centered outcomes of different treatments. Eventually, we will analyse the economic effects of caries and caries treatment, and compare the distributional impact of different treatments in different populations. 

Sjögren’s Syndrome – Consensus and Controversies
Organizer: Gunhild Strand (University of Bergen, Norway)
Sponsor: Unilever Denmark
Location: Lacroma Hotel, Divona Room 1 & 2

Description: Recent studies on Sjögren's syndrome have indicated needs for revision of the current classification criteria, but how do this support the clinician and the researcher in their work with Sjögren' s syndrome? And do they bring us closer to understanding of the pathogenic mechanisms?


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