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Journal of Dental Research Centennial August 2019: The Era of the Genome and Dental Medicine

Alexandria, VA, USA – 2019 marks the Centennial of the Journal of Dental Research (JDR). Over the last century the JDR has been dedicated to the dissemination of new knowledge and information on all sciences relevant to dentistry and to the oral cavity and associated structures in health and disease. To celebrate, the JDR is featuring a yearlong, monthly commemorative article and podcast series that highlights topics that have transformed dental, oral and craniofacial research over the past 100 years.

Understanding the ‘code of life’ and mapping the human genome has been a monumental, era-defining scientific landmark — one that the oral health domain has benefitted from. In the August 2019 issue of the JDR, the article “The Era of the Genome and Dental Medicine” by Kimon Divaris, University of North Carolina at Chapel Hill, USA, reviews the history and landmark developments in the genetics knowledge base of dental and craniofacial health traits and conditions and discusses the future of translating genomics knowledge to genome editing and molecular therapies.

“The oral health domain has made great strides and substantially benefitted from the last century of advances in genetics and genomics. Observations regarding a hereditary component of dental caries were reported as early as in the 1920s and subsequent breakthroughs were made in the discovery of genetic causes of rare diseases such as ectodermal dysplasias, orofacial clefts and other craniofacial and dental anomalies,” said Divaris.

“Gene therapies and gene editing using CRISPR-Cas represent the latest frontier surpassed in the era of genomic medicine but amidst rapid genomics progress, several challenges and opportunities lie ahead. Systematic efforts supported by implementation science are needed for the realization of genomics’ full potential, including the improvement of public and practitioner genomics literacy, the promotion of individual and population oral health and the reduction of health disparities.”

The ninth JDR Centennial podcast, titled article “The Era of the Genome and Dental Medicine” features a conversation between Divaris, Harold Slavkin, University of Southern California, Los Angeles, USA and JDR Editor-in-Chief William Giannobile, University of Michigan, Ann Arbor.

Throughout 2019 JDR Associate Editor, Nicholas Jakubovics, Newcastle University, England, shares ‘Historical Highlights’ and archival excerpts from the rich history of research findings published in the JDR. In the August 2019 issue, Jakubovics highlights the article “The Surface Area of the Adult Human Mouth and Thickness of the Salivary Film Covering the Teeth and Oral Mucosa” (Collins L.M.C., Dawes C. 1987. The Surface Area of the Adult Human Mouth and Thickness of the Salivary Film Covering the Teeth and Oral Mucosa. J Dent Res. 66:1300-1302). The mouth contains many different tissues, each with its own complex anatomic features. Measuring the total surface area inside the mouth is no easy task, but measurements of the tissue surface area are needed to calculate the uptake of drugs through oral tissues, to estimate the total burden of microorganisms attached to surfaces in the oral cavity and to assess the thickness of salivary film covering oral tissues. Overall, this study provided key information on oral tissues that has been incorporated into a broad range of research, from physiology to microbiology, immunology, nutrition and pharmacology.

Along with the article and podcast series, the legacy of the JDR was honored during a celebration at the 97th General Session of the IADR, held in conjunction with the 48th Annual Meeting of the AADR and the 43rdAnnual Meeting of the Canadian Association for Dental Research, in Vancouver, British Columbia, Canada on June 19-22, 2019. For more information on the JDR Centennial, please visit: www.iadr.org/JDRcentennial.

About the Journal of Dental Research
The IADR/AADR Journal of Dental Research (JDR) is a multidisciplinary journal dedicated to the dissemination of new knowledge in all sciences relevant to dentistry and the oral cavity and associated structures in health and disease. The JDR continues to rank #1 of 90 journals in Eigenfactor with a score of 0.021290, ranks #2 in Impact Factor of 90 journals in the “Dentistry, Oral Surgery & Medicine” category at 5.125 and ranks #2 of 90 in Article Influence with a score of 1.643.The JDR’s 5-year Impact Factor has remained above 5 for the fourth year at 5.722, ranking #2 of 91 journals. With over 20,000 citations, the JDR also boasts the most citations in the “Dentistry, Oral Surgery & Medicine” category — 4,500 citations above the second ranked journal in the field.

International Association for Dental Research

The International Association for Dental Research (IADR) is a nonprofit organization with over 11,400 individual members worldwide, with a Mission to drive dental, oral and craniofacial research to advance health and well-being worldwide. To learn more, visit www.iadr.org. The American Association for Dental Research (AADR) is the largest Division of IADR with 3,300 members in the United States. To learn more, visit www.iadr.org/aadr.

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