Alexandria, VA, USA – 2019 marks the Centennial of the Journal of Dental Research (JDR). Over the last century the JDR has been dedicated to the dissemination of new knowledge and information on all sciences relevant to dentistry and to the oral cavity and associated structures in health and disease. The June 2019 issue of the JDR features the article “A Century of Change Towards Prevention and Minimal Intervention in Cariology” by Nicola Innes, University of Dundee, Scotland, Chun Chu, University of Hong Kong, SRA, China, Margherita Fontana, University of Michigan, Ann Arbor, USA, Edward Lo, University of Hong Kong, SRA, China, Murray Thomson, The University of Otago, Dunedin, New Zealand, Sergio Uribe, Universidad Austral de Chile, Valdivia, Max Heiland, Charité-Universitätsmedizin Berlin, Germany, Sören Jespen, University of Bonn, Germany and Falk Schwendicke, Charité – Universitätsmedizin Berlin, Germany.