U.S. NIH Funding Opportunities
NIDCR

NOT-DE-20-022: Availability of Urgent Competitive Revisions and Administrative Supplements for Coronavirus Disease 2019 (COVID-19) Research within the Mission of NIDCR

• Allows for within (admin supp) and out of scope (competitive revision) projects to existing NIDCR grants (only a subset of mechanisms are eligible). Emphasis is on immediate and high impact research to protect and ensure the safety of personnel and patients in dental practices, prevent SARS-COV-2 transmission and improve detection and diagnosis of COVID-19, and understand SARS-CoV-2 pathogenesis
• Application due date: November 2, 2020, by 5:00 PM local time of applicant organization.

NOT-DE-20-023: Infrastructure Access for Research on Coronavirus Disease 2019 (COVID-19) Conducted in the National Dental Practice-Based Research Network

• Allows researchers to tap into the PBRN with COVID-19 research
• Application due date: November 2, 2020, by 5:00 PM local time of applicant organization.

NOT-DE-20-024: Notice of Additional Receipt Dates for PAR-20-073 National Dental Practice-Based Research Network Infrastructure Access (X01 Clinical Trial Not Allowed)

• This notice adds two receipt dates for the PBRN X01 PAR to align with the NOT-DE-20-022 dates.
• Application due dates: September 1, 2020, November 2, 2020, September 1, 2021, and September 1, 2022., by 5:00 PM local time of applicant organization.

NOT-OD-20-120: Notice of Special Interest (NOSI): Emergency Competitive Revisions for Community-Engaged Research on COVID-19 Testing among Underserved and/or Vulnerable Population

• This Notice of Special Interest (NOSI) highlights the urgent need to understand and address COVID-19 morbidity and mortality disparities among underserved and vulnerable populations across the United States.
• Expiration Date: September 09, 2020

NOT-OD-20-119: Notice of Special Interest (NOSI): Emergency Competitive Revisions for Social, Ethical, and Behavioral Implications (SEBI) Research on COVID-19 Testing among Underserved and/or Vulnerable Populations

• This Notice of Special Interest (NOSI) highlights the urgent need to understand the social, ethical, and behavioral implications (SEBI) of COVID-19 testing among underserved and/or vulnerable populations across the United States through the Rapid Acceleration of Diagnostics for Underserved Populations (RADx-UP) initiative.
• Expiration Date: September 09, 2020

NOT-OD-20-152: Notice of Special Interest (NOSI): Availability of Emergency Competitive Revisions for Chemosensory Testing as a COVID-19 Screening Tool

• The goal of the RADx-rad initiative is to encourage the development of novel, non-traditional approaches to identify the current SARS-CoV-2 virus or other markers of the COVID-19 disease that can be used in future outbreaks of COVID-19 and that could be applicable to other, as yet unknown, viruses.
• Specifically, the goal of this NOSI is to solicit proposals to enhance the utility of chemosensory testing as a COVID-19 screening tool by using objective tests to examine the onset and prognostic value of chemosensory loss and to encourage the development and/or deployment of home-based and on-site chemosensory tests.
• Application due date: September 15, 2020 by 5:00 PM local time of applicant organization.

RFA-OD-20-016: Emergency Awards: RADx-RAD Multimodal COVID-19 surveillance methods for high risk clustered populations (R01 Clinical Trial Optional)

• This FOA invites applications to pursue development and validation studies of COVID-19 surveillance methods, not based or focused on direct viral testing of individuals, in settings and institutions, including residential, with a high density of individuals who are together for prolonged periods of time.
• Letter of Intent: August 30, 2020
• Application Due: September 30, 2020

RFA-OD-20-018: Emergency Awards: Exosome-based Non-traditional Technologies Towards Multi-Parametric and Integrated Approaches for SARS-CoV-2 (U18 Clinical Trial Not Allowed)

• This emergency FOA provides an expedited funding mechanism as part of the Rapid Acceleration of Diagnostics-Radical (RADx-rad) initiative.
• Specifically, this FOA seeks to use developed technologies for single vesicle or exosome isolation and analysis and reposition these technologies for the detection of SARS-CoV-2.
• Letter of Intent: August 18, 2020
• Application Due: September 18, 2020

RFA-OD-20-017: Emergency Awards RADx-RAD: Screening for COVID-19 by Electronic-Nose Technology (SCENT) (U18 Clinical Trial Not Allowed)

• This emergency FOA provides an expedited funding mechanism as part of the Rapid Acceleration of Diagnostics-Radical (RADx-rad) initiative. Specifically, this FOA seeks to fund a single cooperative agreement for a Data Coordination Center (DCC) to serve as a communication center and data hub for RADx-rad awardees.
• Specifically, this FOA is seeking applications for a portable sensing device to detect volatile organic compounds (VOCs, i.e., scents or odors) emanating from skin or exhaled breath, saliva and different oral tissues from the oral cavity.
• Letter of Intent: August 18, 2020
• Application Due: September 18, 2020

RFA-OD-20-020: Emergency Awards RADx-RAD: Novel Biosensing for Screening, Diagnosis and Monitoring of COVID-19 from Skin and the Oral Cavity (R44 Clinical Trial Not Allowed)

• This emergency FOA provides an expedited funding mechanism as part of the Rapid Acceleration of Diagnostics-Radical (RADx-rad) initiative.
• The goal of this RFA is to solicit Direct to Phase II SBIR applications to advance development of novel, non-traditional, safe and effective biosensing and detection approaches to identify the current SARS-CoV-2 virus or other biomarkers of the COVID-19 disease for use in outbreaks of COVID-19, as well as for use in future pandemics resulting from unknown viruses.
• Letter of Intent: August 18, 2020
• Application Due: September 18, 2020

RFA-OD-20-021: Emergency Awards RADx-RAD: Novel Biosensing for Screening, Diagnosis and Monitoring of COVID-19 from Skin and the Oral Cavity (Fast-Track STTR Clinical Trial Not Allowed)

• This emergency FOA provides an expedited funding mechanism as part of the Rapid Acceleration of Diagnostics-Radical (RADx-rad) initiative.
• The goal of this RFA is to solicit Fast-Track STTR applications to advance development of novel, non-traditional, safe and effective biosensing and detection approaches to identify the current SARS-CoV-2 virus or other biomarkers of the COVID-19 disease for use in outbreaks of COVID-19, as well as for use in future pandemics resulting from unknown viruses.
• Letter of Intent: August 18, 2020
• Application Due: September 18, 2020

RFA-OD-20-022: Emergency Awards: Chemosensory Testing as a COVID-19 Screening Tool (U01 Clinical Trial Optional)

• This emergency FOA from the National Institutes of Health (NIH) provides an expedited funding mechanism as part of the Rapid Acceleration of Diagnostics-Radical (RADx-rad) initiative. The goal of the RADx-rad initiative is to encourage the development of novel, non-traditional approaches to identify the current SARS-CoV-2 virus or other markers of the COVID-19 disease that can be used in future outbreaks of COVID-19 and that could be applicable to other, as yet unknown, viruses.
• Specifically, the goal of this FOA is to solicit applications to enhance the utility of chemosensory testing as a COVID-19 screening tool by using objective tests to examine the onset and prognostic value of chemosensory loss and to encourage the development and/or deployment of home-based and on-site chemosensory tests.
• Letter of Intent: Not applicable
• Application Due: September 15, 2020 by 5:00 PM local time of applicant organization.

Research

Through IADR/AADR’s commercial publisher, all Journal of Dental Research and JDR Clinical & Translational Research COVID-19 related articles will be made freely available on the SAGE Publishing Coronavirus (COVID-19) Research microsite that highlights both social and behavioral sciences and medical sciences research on COVID-19 and more broadly on managing pandemics. This collection includes the latest medical research from SAGE related to the virus as well as top social and behavioral research to help individuals, communities, and leaders make the best decisions on dealing with the outbreak and its consequences. Included in the collection is the recently published “Coronavirus Disease 2019 (COVID-19): Emerging and Future Challenges for Dental and Oral Medicine” by Meng, Hue, and Bian of Wuhan University. SAGE Publishing has also signed and committed to the Wellcome coordinated statement on Sharing research data and findings relevant to the novel coronavirus (COVID-19) outbreak.

Association News

AADR COVID-19 Webinar with NIDCR for Research Deans and Deans
• PowerPoint Slides
• Webinar Recording
• Chat Log
IADR/AADR Covid-19 Resource Blog
IADR Virtual Council Highlights
AADR Virtual Council Highlights

AADR COVID Webinar Series

AADR COVID-19 WebEx with NIDCR for Research Deans and Deans (April 13, 2020)
COVID-19 and Oral Health: Impacts on Care and Early Insights to Pathogenesis (July 22, 2020)
COVID-19 Research Questions and Our Practice From the Wuhan Experience (July 29, 2020)
The Scientific Basis for Delivering Oral Health Care During COVID-19 August 5, 2020

COVID-19 Articles Published in JDR or JDR CTR

Oropharyngeal Secretion as Alternative for SARS-CoV-2 Detection
by C. Yu, L. Li, Y. Tuersun, X. Zhao, Q. Feng, T. Zhang, F.R. Tay and J. Ma
Coronavirus Disease 2019 (COVID-19): Emerging and Future Challenges for Dental and Oral Medicine
by L. Meng, F. Hue, and Z. Bian
COVID-19 Transmission in Dental Practice: Brief Review of Preventive Measures in Italy
by R. Izzetti, M. Nisi, M. Gabriele, and F. Graziani
Dental Care and Oral Health under the Clouds of COVID-19
by E. Eliav, H. Malmstrom, L. Rasubala, and Y.F. Ren
Viral Load Dynamics in Sputum and Nasopharyngeal Swab in Patients with COVID-19
by R. Liu, S. Yi, J. Zhang, C. Zhu, and Y. Zhang

COVID-19 Articles from other Publications

Aerosol and Surface Distribution of Severe Acute Respiratory Syndrome Coronavirus 2 in Hospital Wards, Wuhan, China, 2020
by Zhen-Dong Guo, Zhong-Yi Wang, Shou-Feng Zhang, Xiao Li, Lin Li, Chao Li, Yan Cui, Rui-Bin Fu, Yun-Zhu Dong, Xiang-Yang Chi, Meng-Yao Zhang, Kun Liu, Cheng Cao, Bin Liu, Ke Zhang, Yu-Wei Gao, Bing Lu, and Wei Chen
A medRxiv Preprint: Saliva is more sensitive for SARS-CoV-2 detection in COVID-19 patients than nasopharyngeal swabs.
by Anne Louise Wylie et al.
Coronavirus Disease 19(COVID-19): Implications for Clinical Dental Care
by Amber Ather, Biraj Patel, Nikita B. Ruparel, Anibal Diogenes, and Kenneth M. Hargreaves
Dentistry and coronavirus (COVID-19) - moral decision-making
by Paul Coulthard
High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa
by Hao Xu, Liang Zhong, Jiaxin Deng, Jiakuan Peng, Hongxia Dan, Xin Zeng, Taiwen Li and Qianming Chen
Physical distancing, face masks, and eye protection to prevent person-to-person transmission of SARS-CoV-2 and COVID-19: a systematic review and meta-analysis
by Derek K Chu, Elie A Akl, Stephanie Duda, Karla Solo, Sally Yaacoub, and Holger J Schünemann on behalf of the COVID-19 Systematic Urgent Review Group Effort (SURGE) study authors.
Transmission routes of 2019-nCoV and controls in dental practice
by Xian Peng, Xin Xu, Yuqing Li, Lei Cheng, Xuedong Zhou and Biao Ren  

Other Resources

AADR Proposed COVID-19 Research Agenda (April 2020)
Bioethics Guidance for Hospitals and Healthcare Providers
Canadian Institutes of Health Research (CIHR)
CDC Interim Infection Prevention and Control Guidance for Dental Settings During the COVID-19 Response
COVID-19 Health Literacy Project
National Academies of Sciences, Engineering, and Medicine Webinars
National Institutes of Health (NIH)
• NIH Training for COVID-19 workers to protect their own health
• Information for NIH Applicants and Recipients of NIH Funding
• Virtual Activities for trainees outside of the NIH
U.S. Centers for Disease Control (CDC)
U.S. HHS Guidance on Human Subjects Related to Covid-19
U.S. OSHA COVID-19 Resource page
U.S. OSHA Guidance for Dentistry Workers and Employers
World Health Organization (WHO)
World Health Organization: Considerations for the provision of essential oral health services in the context of COVID-19