Alexandria, VA, USA – A Hands-on Workshop introducing the Updated Human Salivary Proteome (HSP) Wiki was presented at the 102nd General Session of the IADR, which was held in conjunction with the 53rd Annual Meeting of the American Association for Dental, Oral, and Craniofacial Research and the 48th Annual Meeting of the Canadian Association for Dental Research, on March 13-16, 2024, in New Orleans, LA, USA.
The information accumulated in the literature about salivary proteins, their expression, function, and role in health and disease has been made available by establishing the Human Salivary Proteome Wiki. The HSP Wiki serves as a public data platform for researching, retrieving, and annotating custom-curated data and knowledge on the saliva proteome. It is dynamically compiled and updated based on published saliva proteome studies and protein reference records from whole saliva and glandular salivary secretions, and it integrates a wide range of available information by funneling data from established external protein, genome, transcriptome, and glycome databases. This workshop explored how the HSP Wiki will pave the way for harnessing the full potential of the salivary proteome for diagnosis, risk prediction, therapy of oral and systemic diseases, and preparedness for emerging infectious diseases.
The HSP Wiki has recently been transitioned from the National Institute of Dental and Craniofacial Research (NIDCR) to a cloud-based server accessible at https://www.salivaryproteome.org. Novel computational infrastructures for salivary proteomic datasets, including visual analytics, faster processing, and an intuitive user interface, have been added. Future efforts will include integrating the Human Oral Microbiome Database (HOMD) to provide the research community with enhanced tools for analyzing host-microbial interactions. As a community-based data- and knowledgebase, the HSP Wiki will be a worldwide platform to exchange salivary proteome information, inspire novel research ideas, and foster cross-discipline collaborations. Organized by Stefan Ruhl, the Hands-on Workshop, “A Sneak-Peak of the Updated Human Salivary Proteome Wiki” took place on Thursday, March 14, 2024 at 2 p.m. Central Standard Time (UTC-6).
About IADR
The International Association for Dental, Oral, and Craniofacial Research (IADR) is a nonprofit organization with a mission to drive dental, oral, and craniofacial research for health and well-being worldwide. IADR represents the individual scientists, clinician-scientists, dental professionals, and students based in academic, government, non-profit, and private-sector institutions who share our mission. Learn more at www.iadr.org.
About AADOCR
The American Association for Dental, Oral, and Craniofacial Research (AADOCR) is a nonprofit organization with a mission to drive dental, oral, and craniofacial research to advance health and well-being. AADOCR represents the individual scientists, clinician-scientists, dental professionals, and students based in academic, government, non-profit, and private-sector institutions who share our mission. AADOCR is the largest division of IADR. Learn more at www.aadocr.org.